Melanocortin 4 receptor agonists activate obesity-related hypertension

A cellular correlation between melanocortin 4 receptor agonists and their role in obesity-associated hypertension has been identified, according to data published in Cell.“Obesity is a major risk factor for cardiovascular disease, with recent statistics showing that obese adults are three to four times more likely to develop high blood pressure,” study researcher Nina Balthasar, PhD, from the school of physiology and pharmacology at the University of Bristol, United Kingdom, said in a press release. “In order to curb the escalating incidence of obesity and obesity-related diseases, a primary prevention goal must be to understand the physiological processes underlying our vulnerability to weight gain — knowledge that is central to the development of novel, effective therapies.”







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