tPA displayed potential as adjuvant therapy for calciphylaxis

Thrombolytic tissue plasminogen activator demonstrated the possibility of being a useful adjunctive treatment for patients with calciphylaxis, according to recent study results.Researchers at Mayo Clinic, Rochester, Minn., conducted a retrospective chart review of 15 patients with calciphylaxis (median age at diagnosis, 59 years; 11 women) who were treated between 2002 and 2010. The usually fatal thrombotic condition, affecting up to 4% of long-term dialysis patients, results in ischemia, necrosis and infarction of adipose and cutaneous tissue.







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